DOMINO

DOMINO is an active module identification algorithm (which is broadly categorized in SPRAS under ‘disease mining algorithms’). See the associated paper: https://doi.org/10.15252/msb.20209593 and the associated MIT-licensed codebase: https://github.com/Shamir-Lab/DOMINO/.

DOMINO has two optional parameters:

• slice_threshold: the p-value threshold for considering a slice as relevant

• module_threshold: the p-value threshold for considering a putative module as final module